Extracellular Vesicles: Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine (Adv. Sci. 2/2018)

Extracellular Vesicles: Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine (Adv. Sci. 2/2018)

Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine

Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles consisting of a lipid bilayer enclosing proteins and nucleic acids, which are active in intercellular communications. EVs are increasingly seen as a vital component of many biological functions that were once considered to require the direct participation of stem cells. Consequently, transplantation of EVs is gradually beco...

Extracellular Vesicles in Regenerative Medicine, a Brief Review

Extracellular vesicles were initially known as cellular waste carriers, while recent studies demonstrate that extracellular vesicles play important biological roles in all aspects of life-from single cells to mammalians. Their pathophysiological roles in some diseases like cancer are being decoded. Extracellular vesicles are divided into some classes and there are different strategies to isolat...

EXTRACELLULAR VESICLES AND THEIR THERAPEUTIC APPLICATIONS: A REVIEW

Background & Aims: Extracellular vesicles are double phospholipid layer vesicles releasing from several cells.  These particles contain bio-molecules including mRNA, miRNA, DNA, proteins, and lipids which play a pivotal role in the cell to cell communication. Once delivered, they participate to change target cell function, fate, morphology, differentiation, and growth. The present study is a re...

Isolation and characterization of Faecalibacterium prausnitzii extracellular vesicles

Introduction: Extracellular vesicles (EVs) contain active biological compounds which play important roles in biological processes. The secretion of EVs is a common phenomenon which occurs in archaea, bacteria and mammalian cells. The secretion of bacterial EVs has been discovered in various species of both Gram-negative and Gram-positive bacteria. Faecalibacterium prausnitzii is one of the comm...